In the fast-growing, cutting-edge fields of cancer immunology, stem cell research, and the development of cell-based formulations, understanding cellular metabolism has never been more critical. Enter LiCellMo, the groundbreaking live cell metabolic analyzer. This new product from PHCbi brand is designed to provide continuous, sample-free measurement of glucose and lactate in culture mediums, offering unprecedented real-time insights into cell metabolism.
Real-Time Live Cell Metabolic Analysis with In-Line Sensors
Traditional live cell metabolic analysis relies on periodic sampling to estimate glucose and lactate levels. PHCbi LiCellMo changes the game with its high-precision In-Line sensors, enabling:
- Real-time monitoring of glucose and lactate concentrations
- Continuous, sample-free measurements preserving cells for further analysis
- Comprehensive, quantifiable data for detailed metabolic evaluation
These capabilities open new avenues for discovering metabolic behaviors linked to cell growth, differentiation, and disease progression.
Seamless Integration into Standard Lab Environments
LiCellMo’s design prioritizes simplicity and flexibility:
- Compatible with common commercial products like standard culture mediums and 24-well plates
- Single-use sensor modules and plate adapters attach easily to standard 24-well plates
- Real-time monitoring via a touch-panel controller within a CO2 incubator
Optional plate adapters support five different commercial 24-well plate types, making LiCellMo adaptable to diverse lab setups.
Direct Evaluation of Glycolytic Changes
LiCellMo excels in evaluating glycolytic pathways by:
- Measuring glucose uptake and lactate production directly in the culture medium
- Visualizing metabolism through consumption and production rates
- Assessing not just glycolysis but also its interplay with the TCA cycle and oxidative phosphorylation
These insights are invaluable for understanding cellular energy efficiency and metabolic shifts in various research contexts.
LiCellMo (Live Cell Metabolic) Analyzer Product Summary
- Monitored Items: Glucose, Lactate (simultaneous continuous measurement)
- Components: Controller, Detector, Plate Adapter (optional)
- Consumables: Single-use Sensor Module
- Compatible Plates: 24-well plates (5 commercial types supported)
- Monitoring Duration: Up to 10 days
Measurement Ranges:
- Glucose: 1 to 27 mM (0.18 to 4.86 g/L)
- Lactate: 1.5 to 15 mM (0.14 to 1.35 g/L)
Controller Specifications:
- Dimensions: 371 mm (W) × 200 mm (D) × 295 mm (H)
- Weight: 2.5 kg
- Display: 15.6-inch touch panel
- Connectivity: Supports up to 4 detectors
Detector Specifications:
- Dimensions: 162 mm (W) × 290 mm (D) × 118 mm (H)
- Weight: 4.7 kg
- Installation: Inside CO2 incubator
- Capacity:
- MCO-50 series: Max. 1 unit
- MCO-170/171/230 series: Max. 4 units (2 tiers of 2 units)
Unlock New Discoveries with PHCbi LiCellMo
PHCbi LiCellMo isn’t just an analyzer; it’s a gateway to deeper understanding of cellular metabolism. Its real-time, continuous monitoring capabilities will transform how researchers visualize and interpret metabolic processes, paving the way for groundbreaking discoveries in life sciences.
Frequently Asked Questions: PHCbi LiCellMo™ Live-Cell Metabolic Analyzer
The LiCellMo™ is a live-cell metabolic analyzer offering continuous, real-time monitoring of glucose uptake and lactate production right in your CO₂ incubator. It uses in-line electrochemical sensors to measure glycolysis minute-by-minute without the need for sampling, ensuring seamless analysis of cellular metabolic pathways.
Unlike periodic sampling, LiCellMo™ provides uninterrupted metabolic data, reducing contamination risk and preserving the same live cells for further experimentation. This technology captures dynamic metabolic changes that might be missed by intermittent sampling.
By offering minute-by-minute insights, LiCellMo™ empowers researchers to detect subtle metabolic shifts, optimize culture conditions, and make informed decisions in fields like cancer immunology, stem cell research, and cell and gene therapy. It enhances experimental precision and accelerates discovery.
Designed for compatibility, LiCellMo™ integrates easily into existing CO₂ incubators and uses standard 24-well plates and culture media. Optional adapters fit a variety of commercial plate formats, facilitating adoption without requiring specialized infrastructure.
The system comprises a sensor module with in-line electrochemical sensors, a detector for incubator installation, and a touch-panel controller. Glucose and lactate are measured simultaneously via enzymatic reactions converted into electrical signals, offering precise, continuous metabolic profiling.
LiCellMo™ is ideal for live-cell metabolic analysis in regenerative medicine, disease modeling, therapeutic development, immune cell metabolism studies, and differentiation assessments. It enables tracking of metabolic trends in real time under normal culture conditions.
