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Laboratory Freeze Dryers

LabRepCo is an authorized Labconco distributor offering the complete FreeZone freeze dryer lineup, the most widely used laboratory lyophilizer series in North American research, pharmaceutical, and biotech facilities. Our catalog covers the full FreeZone range: benchtop models from 2.5 to 8 liters and console systems from 6 to 18 liters, with collector temperatures from -50°C to -105°C and configurations both with and without integrated Stoppering Tray Dryers for vial stoppering under vacuum.

Freeze drying, also called lyophilization, removes water from biological, chemical, and food samples by first freezing the material and then sublimating the ice under high vacuum, converting it directly from solid to vapor without passing through the liquid phase. This low-temperature, low-pressure process preserves heat-sensitive compounds, proteins, enzymes, biologics, and microorganisms far more effectively than conventional heat-based drying methods, extending shelf life while maintaining potency, solubility, and structural integrity.

Every Labconco FreeZone model includes the Lyo-Works OS on a 5-inch full-color capacitive touchscreen, displaying real-time collector temperature and vacuum level, programmable drying cycles, and data logging with USB and Ethernet export. All models require a separately purchased vacuum pump (98 L/min minimum displacement, 0.002 mBar ultimate pressure, 3/4″ ID hose fitting). Contact your LabRepCo regional representative for pump pairing guidance, accessory recommendations, and formal quotes.

Laboratory Freeze Dryers

How to Choose the Right Freeze Dryer

Four decisions determine the right FreeZone model for your application:

  • Collector capacity (liters): How much ice will accumulate from your samples per run? Select a collector 10–15% larger than your estimated ice load to avoid overloading and incomplete drying cycles. Benchtop models: 2.5, 4.5, or 8 liters. Console models: 6, 12, or 18 liters.
  • Collector temperature (-50°C vs. -84°C vs. -105°C): Match the collector temperature to the eutectic point of your samples. -50°C models handle aqueous (water-based) samples. -84°C models extend coverage to samples with acetonitrile and other organic solvents with lower eutectic points. -105°C is required for the lowest eutectic point samples including dilute methanol and ethanol mixtures, and for samples requiring the deepest possible collector temperature margin.
  • Benchtop vs. console: Benchtop freeze dryers (2.5–8L) sit on a lab bench and connect to a drying accessory via the top port. Console freeze dryers (6–18L) have an integrated cabinet with interior space for the vacuum pump, a front viewing window, and can accept full-size Stoppering Tray Dryers. Console models are generally preferred for pharmaceutical and production environments.
  • Stoppering Tray Dryer: Required if you need to stopper vials or serum bottles under vacuum at the end of the drying cycle — a standard step in pharmaceutical lyophilization. Console models are available as freeze dryer only (no stoppering) or with an integrated FreeZone Stoppering Tray Dryer. The Stoppering Tray Dryer adds temperature-controlled shelves, a pneumatic stoppering mechanism, and a purge valve for inert gas backfill.

Full Product Comparison Table

Model Type Collector (L) Collector Temp Sample Type Stoppering? Item #
FreeZone 2.5L -50°C Benchtop Benchtop 2.5 L -50°C Aqueous No 700201000
FreeZone 2.5L -84°C Benchtop Benchtop 2.5 L -84°C Low eutectic / acetonitrile No 710201000
FreeZone 4.5L -50°C Benchtop Benchtop 4.5 L -50°C Aqueous No 700402040
FreeZone 4.5L -84°C Benchtop Benchtop 4.5 L -84°C Low eutectic / acetonitrile No 710401000
FreeZone 4.5L -105°C Benchtop Benchtop 4.5 L -105°C Lowest eutectic / methanol, ethanol No 720401000
FreeZone 8L -50°C Benchtop Benchtop 8 L -50°C Aqueous, high load No 700801000
FreeZone 6L -50°C Console Console 6 L -50°C Aqueous No 700611000
FreeZone 6L -50°C Console + Stoppering Console 6 L -50°C Aqueous YES 700621000
FreeZone 6L -84°C Console Console 6 L -84°C Low eutectic No 710611000
FreeZone 6L -84°C Console + Stoppering Console 6 L -84°C Low eutectic YES 710621000
FreeZone 12L -50°C Console Console 12 L -50°C Aqueous, high throughput No 701211210
FreeZone 12L -50°C Console + Stoppering Console 12 L -50°C Aqueous, high throughput YES 701221010
FreeZone 12L -84°C Console + Stoppering Console 12 L -84°C Low eutectic, high throughput YES 711221010
FreeZone 18L -50°C Console Console 18 L -50°C Aqueous, production scale No 701811010
FreeZone 18L -50°C Console + Stoppering Console 18 L -50°C Aqueous, production scale YES 701821010

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